catalog number :
MBS120095
products full name :
Mouse monoclonal antibody Anti-Human p66alpha
products short name :
p66alpha
products name syn :
Homo sapiens GATA zinc finger domain containing 2A (GATAD2A), mRNA; FLJ20085;GATAD2A
other names :
Homo sapiens GATA zinc finger domain containing 2A (GATAD2A), transcript variant 2, mRNA; Transcriptional repressor p66-alpha; transcriptional repressor p66-alpha; GATA zinc finger domain-containing protein 2A; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A
products gene name :
p66alpha
other gene names :
GATAD2A; GATAD2A; p66alpha
uniprot entry name :
P66A_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Transcriptional repressor{EC1}. [UniProtKB Function]
ncbi acc num :
NP_060130.3
ncbi gb acc num :
NM_017660
ncbi mol weight :
68,134 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); Gene Expression Pathway (105937); HDACs Deacetylate Histones Pathway (1127684); RNA Polymerase I Promoter Clearance Pathway (106551); RNA Polymerase I Transcription Pathway (106550); RNA Polymerase I Transcription Initiation Pathway (106553); RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway (160948); Signaling Events Mediated By HDAC Class I Pathway (137997)
uniprot summary :
GATAD2A: Transcriptional repressor. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 19p13.11. Cellular Component: nucleoplasm; nuclear speck; NuRD complex; nucleus. Molecular Function: protein binding, bridging; protein binding; zinc ion binding; sequence-specific DNA binding; transcription factor activity. Biological Process: blood vessel development; embryonic body morphogenesis; neural fold formation; anterior neuropore closure; transcription, DNA-dependent; in utero embryonic development; programmed cell death; DNA methylation; negative regulation of transcription, DNA-dependent