product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human EIF2S1
catalog :
MBS120093
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
EIF2S1A2B8
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120093
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human EIF2S1
products short name :
EIF2S1
products name syn :
Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, mRNA (cDNA clone MGC:1511 IMAGE:3139624), complete cds; EIF-2A; EIF-2alpha; EIF-2; EIF2A
other names :
Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, mRNA; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1; eIF-2-alpha; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha
products gene name :
EIF2S1
other gene names :
EIF2S1; EIF2S1; EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha
uniprot entry name :
IF2A_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
EIF2S1A2B8
host :
Mouse
reactivity :
Human
sequence length :
2983
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi gi num :
33876800
ncbi acc num :
BC002513
ncbi mol weight :
36,112 Da
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway 105970!!BDNF Signaling Pathway 712093!!Cap-dependent Translation Initiation Pathway 105967!!Eukaryotic Translation Initiation Pathway 105966!!Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway 105969!!GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway 105973!!Gene Expression Pathway 105937!!Hepatitis C Pathway 173973!!Hepatitis C Pathway 173907!!Herpes Simplex Infection Pathway 377873
ncbi summary :
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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