catalog number :
MBS120071
products full name :
Mouse monoclonal antibody Anti-Human LHX2
products short name :
LHX2
products name syn :
LIM homeobox 2; LH2; hLhx2
other names :
Homo sapiens LIM homeobox 2, mRNA; LIM/homeobox protein Lhx2; LIM/homeobox protein Lhx2; LIM HOX gene 2; LIM homeobox protein 2; homeobox protein LH-2; LIM homeobox 2
products gene name :
LHX2
other gene names :
LHX2; LHX2; LH2; hLhx2
uniprot entry name :
LHX2_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [NCBI Entrez Gene Summary]
ncbi mol weight :
44,373 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460)
ncbi summary :
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]
uniprot summary :
LHX2: Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 9q33.3. Cellular Component: nucleus. Molecular Function: zinc ion binding; sequence-specific DNA binding; chromatin binding. Biological Process: transcription from RNA polymerase II promoter; axon guidance; dorsal/ventral pattern formation; axon extension; retina development in camera-type eye; olfactory bulb development; positive regulation of transcription, DNA-dependent; neural tube closure; mesoderm development; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex development; telencephalon regionalization