catalog number :
MBS120070
products full name :
Mouse monoclonal antibody Anti-Human GATAD1
products short name :
GATAD1
products name syn :
GATA zinc finger domain containing 1 (GATAD1); ODAG; FLJ22489; RG083M05.2
other names :
Homo sapiens GATA zinc finger domain containing 1 (GATAD1), transcript variant 1, mRNA; GATA zinc finger domain-containing protein 1; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATA zinc finger domain containing 1; Ocular development-associated gene protein
products gene name :
GATAD1
other gene names :
GATAD1; GATAD1; ODAG; CMD2B; RG083M05.2
uniprot entry name :
GATD1_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
ncbi acc num :
NP_066990.3
ncbi gb acc num :
NM_021167
ncbi mol weight :
28,690 Da
ncbi summary :
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
uniprot summary :
GATAD1: Component of some chromatin complex recruited to chromatin sites methylated Lys-4 of histone H3 (H3K4me). Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B). CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 7q21-q22. Cellular Component: nucleoplasm; nucleus. Molecular Function: zinc ion binding; sequence-specific DNA binding; transcription factor activity. Biological Process: regulation of transcription, DNA-dependent. Disease: Cardiomyopathy, Dilated, 2b