catalog number :
MBS120060
products full name :
Mouse monoclonal antibody Anti-Human MARS
products short name :
MARS
products name syn :
methionine-tRNA synthetase; MTRNS; METRS
other names :
Homo sapiens methionyl-tRNA synthetase, mRNA; Methionine--tRNA ligase, cytoplasmic; methionine--tRNA ligase, cytoplasmic; cytosolic methionyl-tRNA synthetase; methionyl-tRNA synthetase; Methionyl-tRNA synthetase; MetRS
products gene name :
MARS
other gene names :
MARS; MARS; MRS; METRS; MTRNS; SPG70
uniprot entry name :
SYMC_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene belongs to the class I family of tRNA synthetases. [NCBI Entrez Gene Summary]
ncbi mol weight :
61,816 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway (83030); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (413439); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (105981); Gene Expression Pathway (105937); Selenocompound Metabolism Pathway (82969); Selenocompound Metabolism Pathway (338); TRNA Aminoacylation Pathway (105980)
ncbi summary :
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]
uniprot summary :
MARS: a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]. Protein type: EC 6.1.1.10; Other Amino Acids Metabolism - selenoamino acid; Ligase; Translation. Chromosomal Location of Human Ortholog: 12q13.3. Cellular Component: membrane; mitochondrion; cytoplasm; cytosol. Molecular Function: methionine-tRNA ligase activity; ATP binding; tRNA binding. Biological Process: tRNA aminoacylation for protein translation; methionyl-tRNA aminoacylation; gene expression. Disease: Infantile Liver Failure Syndrome 2; Charcot-marie-tooth Disease, Axonal, Type 2u