catalog number :
MBS120040
products full name :
Mouse monoclonal antibody Anti-Human PYGO2
products short name :
PYGO2
products name syn :
pygopus homolog 2 (Drosophila) (PYGO2); FLJ33226; 1190004M21Rik
other names :
Homo sapiens pygopus family PHD finger 2 (PYGO2), mRNA; Pygopus homolog 2; pygopus homolog 2; pygopus 2; pygopus family PHD finger 2
products gene name :
PYGO2
other gene names :
PYGO2; PYGO2; 1190004M21Rik
uniprot entry name :
PYGO2_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), ELISA (EIA)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Involved in signal transduction through the Wnt pathway. [UniProtKB Function]
ncbi acc num :
NP_612157.1
ncbi gb acc num :
NM_138300
ncbi mol weight :
41,244 Da
ncbi pathways :
Disease Pathway (530764); RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway (1127632); Signal Transduction Pathway (477114); Signaling By WNT In Cancer Pathway (1127614); Signaling By Wnt Pathway (106510); TCF Dependent Signaling In Response To WNT Pathway (1127516); XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway (1127633); Deactivation Of The Beta-catenin Transactivating Complex Pathway (1127521); Formation Of The Beta-catenin:TCF Transactivating Complex Pathway (1127519); Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway (1127631)
uniprot summary :
PYGO2: Involved in signal transduction through the Wnt pathway. Protein type: Cell development/differentiation; Histone-binding. Chromosomal Location of Human Ortholog: 1q21.3. Cellular Component: nucleoplasm. Molecular Function: protein binding; histone acetyltransferase regulator activity; histone binding; zinc ion binding; chromatin binding. Biological Process: lens development in camera-type eye; developmental growth; in utero embryonic development; spermatid nuclear differentiation; regulation of histone acetylation; Wnt receptor signaling pathway through beta-catenin; palate development; post-embryonic development; regulation of mammary gland epithelial cell proliferation; mammary gland development; regulation of histone H3-K4 methylation; brain development; kidney development