product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human TADA3L
catalog :
MBS120039
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TADAD25A
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120039
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human TADA3L
products short name :
TADA3L
products name syn :
transcriptional adaptor 3 (NGG1 homolog, yeast)-like (TADA3L); ADA3; hADA3; FLJ20221; FLJ21329
other names :
Homo sapiens transcriptional adaptor 3 (TADA3), transcript variant 1, mRNA; Transcriptional adapter 3; transcriptional adapter 3; ADA3 homolog; ADA3-like protein; transcriptional adaptor 3; ADA3 homolog; hADA3; STAF54; Transcriptional adapter 3-like; ADA3-like protein
products gene name :
TADA3L
other gene names :
TADA3; TADA3; ADA3; NGG1; hADA3; STAF54; TADA3L
uniprot entry name :
TADA3_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
TADAD25A
host :
Mouse
reactivity :
Human
sequence length :
2530
concentration :
100 ug/ml (1.0 ml)
tested application :
ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [NCBI Entrez Gene Summary]
ncbi gi num :
507417951
ncbi acc num :
NP_006345.1
ncbi gb acc num :
NM_006354
ncbi mol weight :
41,393 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!HATs Acetylate Histones Pathway 1127683
ncbi summary :
DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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