antibody

Mouse monoclonal antibody Anti-Human MYBL2

MBS120032

0.1 mg

345 USD

monoclonal

mouse

nonconjugated

MYBAD10A

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

Mouse monoclonal antibody Anti-Human MYBL2

MYBL2

v-myb myeloblastosis viral oncogene homolog? (avian)-like 2 (MYBL2); BMYB; MGC15600

Homo sapiens v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2), transcript variant 1, mRNA; Myb-related protein B; myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2; v-myb avian myeloblastosis viral oncogene homolog-like 2; Myb-like protein 2

MYBL2

MYBL2; MYBL2; BMYB; B-MYB

MYBB_HUMAN

Monoclonal

IgG1

MYBAD10A

Mouse

Human

2785

100 ug/ml (1.0 ml)

ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB)

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

Sterility: Filtered through a 0.22 um membrane.

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. [NCBI Entrez Gene Summary]

519666781

NP_002457.1

NM_002466

75,865 Da

Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); E2F Transcription Factor Network Pathway (137934); G0 And Early G1 Pathway (477139); G2/M Transition Pathway (105801); Gastric Cancer Network 1 Pathway (760635); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Mitotic G1-G1/S Phases Pathway (160941); Mitotic G2-G2/M Phases Pathway (160942)

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 20q13.1. Cellular Component: nucleoplasm. Molecular Function: protein binding; chromatin binding; transcription factor activity. Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle

0.1 mg

345 USD