catalog number :
MBS120007
products full name :
Mouse monoclonal antibody Anti-Human DBP
products short name :
DBP
products name syn :
albumin D-box binding protein
other names :
Human albumin D-box binding protein mRNA, complete cds; D site-binding protein; albumin D box-binding protein; albumin D-element-binding protein; tax-responsive enhancer element-binding protein 302; taxREB302; D site of albumin promoter (albumin D-box) binding protein
other gene names :
DBP; DABP
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family (Khatib et al., 1994).[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi acc num :
AAB50219.1
ncbi pathways :
BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway (477138); Circadian Clock Pathway (187173)
ncbi summary :
The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
uniprot summary :
DBP: This transcriptional activator recognizes and binds to the sequence 5 -RTTAYGTAAY-3 found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. Belongs to the bZIP family. PAR subfamily. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: nucleus. Biological Process: circadian rhythm; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; liver development