antibody

Mouse monoclonal antibody Anti-Human ABCF1

MBS120004

0.1 mg

345 USD

monoclonal

mouse

nonconjugated

ABC5H06

Antibody

Mouse monoclonal antibody Anti-Human ABCF1

ABCF1

ATP-binding cassette; ABC27

Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 1, mRNA; ATP-binding cassette sub-family F member 1; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50 (TNF-alpha stimulated); TNF-alpha-stimulated ABC protein; TNFalpha-inducible ATP-binding protein; ATP-binding cassette, sub-family F (GCN20), member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein

ABCF1

ABCF1; ABCF1; ABC27; ABC50

ABCF1_HUMAN

Monoclonal

IgG1

ABC5H06

Mouse

Human

3204

100 ug/ml (1.0 ml)

Dot Blot (DB), Immunoprecipitation (IP)

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

Sterility: Filtered through a 0.22 um membrane.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [NCBI Entrez Gene Summary]

34783469

BC034488

91,680 Da

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]

ABCF1: Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding; Translation. Chromosomal Location of Human Ortholog: 6p21.33. Cellular Component: nucleoplasm; polysomal ribosome; membrane; cytoplasm; ribosome; nuclear envelope. Molecular Function: protein binding; translation activator activity; translation factor activity, nucleic acid binding; ATPase activity; ribosome binding; ATP binding. Biological Process: positive regulation of translation; translation; ribosome biogenesis and assembly; translational initiation; inflammatory response

0.1 mg

345 USD