product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human SP1
catalog :
MBS120003
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SP15H09
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120003
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human SP1
products short name :
SP1
products name syn :
Sp1 transcription factor
other names :
Homo sapiens Sp1 transcription factor, mRNA; Transcription factor Sp1; transcription factor Sp1; specificity protein 1; Sp1 transcription factor
products gene name :
SP1
other gene names :
SP1; SP1
uniprot entry name :
SP1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
SP15H09
host :
Mouse
reactivity :
Human
sequence length :
2891
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
ncbi gi num :
38512204
ncbi acc num :
BC062539
ncbi mol weight :
75,824 Da
ncbi pathways :
AGE/RAGE Pathway (698754); Activation Of Gene Expression By SREBF (SREBP) Pathway (685552); Adipogenesis Pathway (198832); Androgen Receptor Signaling Pathway (198806); C-MYB Transcription Factor Network Pathway (138073); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Choline Metabolism In Cancer Pathway (1059539); Choline Metabolism In Cancer Pathway (1084232); Corticotropin-releasing Hormone Pathway (920957)
ncbi summary :
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
uniprot summary :
SP1: a transcription factor of the Sp1 C2H2-type zinc-finger protein family. Phosphorylated and activated by MAPK. Dephosphorylation by PTEN inhibits DNA binding. Binds to p38 in the nucleus. Interacts with Huntingtin and TAFII130. Transcriptional activity of SP1 and TAFII130 disrupted in early Huntingtin s Disease. Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 12q13.1. Cellular Component: nucleoplasm; cytoplasm; nucleus. Molecular Function: protein C-terminus binding; histone acetyltransferase binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; metal ion binding; histone deacetylase binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor binding; transcription factor activity. Biological Process: transcription initiation from RNA polymerase II promoter; ossification; embryonic placenta development; transcription, DNA-dependent; viral reproduction; megakaryocyte differentiation; embryonic skeletal development; positive regulation of transcription, DNA-dependent; embryonic process involved in female pregnancy; rhythmic process; cellular lipid metabolic process; enucleate erythrocyte differentiation; liver development; trophectodermal cell differentiation; regulation of transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; gene expression; embryonic camera-type eye morphogenesis; lung development
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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