product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human BTAF1
catalog :
MBS120002
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BTA3D61
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120002
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human BTAF1
products short name :
BTAF1
products name syn :
BTAF1 RNA polymerase II, B-TFIID transcription?factor-associated, 170kDa (Mot1 homolog, S. cerevisiae) (BTAF1); MOT1; TAF172; KIAA0940; TAFII170;TAF(II)170
other names :
Homo sapiens BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (BTAF1), mRNA; TATA-binding protein-associated factor 172; TATA-binding protein-associated factor 172; ATP-dependent helicase BTAF1; B-TFIID transcription factor-associated 170 kDa subunit; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); TBP-associated factor 172; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa; ATP-dependent helicase BTAF1; B-TFIID transcription factor-associated 170 kDa subunit; TAF(II)170; TBP-associated factor 172; TAF-172
products gene name :
BTAF1
other gene names :
BTAF1; BTAF1; MOT1; TAF172; TAFII170; TAF(II)170
uniprot entry name :
BTAF1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
BTA3D61
host :
Mouse
reactivity :
Human
sequence length :
7054
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi gi num :
50345994
ncbi acc num :
NP_003963.1
ncbi gb acc num :
NM_003972
ncbi mol weight :
76,419 Da
ncbi summary :
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]
uniprot summary :
TAF172: Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner. Associates with TBP to form B-TFIID. Binds DRAP1. Belongs to the SNF2/RAD54 helicase family. Protein type: Helicase; EC 3.6.4.-; EC 3.6.1.-; Transcription initiation complex. Chromosomal Location of Human Ortholog: 10q22-q23. Cellular Component: nucleus. Molecular Function: DNA binding; helicase activity; transcription factor activity; ATP binding. Biological Process: metabolic process; negative regulation of transcription, DNA-dependent
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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