catalog number :
MBS1198556
products type :
Recombinant Protein
products full name :
Recombinant Mouse C-C motif chemokine 25 (Ccl25)
products short name :
C-C motif chemokine 25 (Ccl25)
products name syn :
C-C motif chemokine 25; Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokine
other names :
C-C motif chemokine 25; C-C motif chemokine 25; C-C motif chemokine 25; thymus-expressed chemokine; small inducible chemokine 25; small inducible cytokine A25; chemokine (C-C motif) ligand 25; Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokine
products gene name :
Ccl25
products gene name syn :
Ccl25; Scya25; Teck
other gene names :
Ccl25; Ccl25; TECK; CKb15; Scya25; AI852536; A130072A22Rik; Scya25; Teck
uniprot entry name :
CCL25_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
24-144
sequence :
QGAFEDC CLGYQHRIKW NVLRHARNYH QQEVSGSCNL RAVRFYFRQK VVCGNPEDMN VKRAMRILTA RKRLVHWKSA SDSQTERKKS NHMKSKVENP NSTSVRSATL GHPRMVMMPR KTNN
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
products description :
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
ncbi acc num :
NP_033164.1
ncbi gb acc num :
NM_009138.3
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1000944); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1000942); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (i) Signalling Events Pathway (1000973); GPCR Downstream Signaling Pathway (1000971); GPCR Ligand Binding Pathway (1000941)
uniprot summary :
CCL25: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Belongs to the intercrine beta (chemokine CC) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis; Secreted. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; chemokine receptor binding; chemokine activity; CCR10 chemokine receptor binding; cytokine activity. Biological Process: G-protein coupled receptor protein signaling pathway; immune response; chemotaxis; positive regulation of cell-matrix adhesion; inflammatory response; leukocyte migration
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)