product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Stimulated by retinoic acid gene 6 protein (Stra6)
catalog :
MBS1196556
quantity :
1 mg (E-Coli)
price :
1260 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1196556
products type :
Recombinant Protein
products full name :
Recombinant Mouse Stimulated by retinoic acid gene 6 protein (Stra6)
products short name :
Stimulated by retinoic acid gene 6 protein (Stra6)
products name syn :
Recombinant Stimulated by retinoic acid gene 6 protein (Stra6); Stimulated by retinoic acid gene 6 protein; Retinoic acid-responsive protein
other names :
stimulated by retinoic acid gene 6 protein; Stimulated by retinoic acid gene 6 protein; stimulated by retinoic acid gene 6 protein; retinoic acid-responsive protein; stimulated by retinoic acid gene 6; Retinoic acid-responsive protein
products gene name syn :
Stra6
other gene names :
Stra6; Stra6; AI891933
uniprot entry name :
STRA6_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
532-670
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Mus musculus (Mouse)
ncbi gi num :
242332599
ncbi acc num :
NP_001155947.1
ncbi gb acc num :
NM_001162475.1
uniprot acc num :
O70491
ncbi mol weight :
73,775 Da
uniprot summary :
STRA6: May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex. Defects in STRA6 are the cause of microphthalmia syndromic type 9 (MCOPS9); also called Matthew-Wood syndrome or Spear syndrome. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS9 is a rare clinical entity including as main characteristics anophthalmia or severe microphthalmia, and pulmonary hypoplasia or aplasia. Mutations in STRA6 may be a cause of isolated colobomatous microphthalmia, a disorder of the eye characterized by an abnormally small ocular globe. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Cellular Component: protein complex; membrane; plasma membrane; integral to membrane. Molecular Function: protein binding; receptor activity; vitamin transporter activity. Biological Process: blood vessel development; developmental growth; adrenal gland development; heart development; neuromuscular process; positive regulation of JAK-STAT cascade; ear development; digestive tract morphogenesis; learning; vocal learning; female genitalia development; nose morphogenesis; smooth muscle development; positive regulation of behavior; transport; artery morphogenesis; feeding behavior; kidney development; cognition; embryonic gut development; alveolus development; lung development
size1 :
1 mg (E-Coli)
price1 :
1260 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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