catalog number :
MBS1191031
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)
products short name :
(Rhesus macaque) Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2)
products name syn :
Recombinant (Rhesus macaque) Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2); Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2
other names :
gamma-aminobutyric acid receptor subunit beta-2; Gamma-aminobutyric acid receptor subunit beta-2; gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2; gamma-aminobutyric acid A receptor beta 2; GABA(A) receptor subunit beta-2
products gene name syn :
GABRB2
other gene names :
GABRB2; GABRB2
uniprot entry name :
GBRB2_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
26-244
sequence :
SVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGM
NIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPL
NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL
HPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY
GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITK
KVVFSTGSYPRLSLSFKLKRNIGY
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi acc num :
NP_001161800.1
ncbi gb acc num :
NM_001168328.1
ncbi mol weight :
59,150 Da
ncbi pathways :
GABAergic Synapse Pathway (377275); GABAergic Synapse Pathway (377129); Morphine Addiction Pathway (552685); Morphine Addiction Pathway (554808); Neuroactive Ligand-receptor Interaction Pathway (86723); Neuroactive Ligand-receptor Interaction Pathway (462); Nicotine Addiction Pathway (583267); Nicotine Addiction Pathway (584676); Retrograde Endocannabinoid Signaling Pathway (537752); Retrograde Endocannabinoid Signaling Pathway (539806)
uniprot summary :
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Subunit structure: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1. Interacts with KCTD8, KCTD12 and KCTD16; this interaction determines the pharmacology and kinetics of the receptor response, the KCTD proteins markedly accelerating the GABA-B response, although to different extents . By similarity. Subcellular location: Cell junction synapse postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily. [View classification]