catalog number :
MBS1173692
products type :
Recombinant Protein
products full name :
Recombinant Mouse Troponin I, cardiac muscle (Tnni3)
products short name :
[Troponin I, cardiac muscle (Tnni3)]
products name syn :
[Troponin I, cardiac muscle; Cardiac troponin I]
other names :
[troponin I, cardiac muscle; Troponin I, cardiac muscle; troponin I, cardiac muscle; cardiac troponin I; troponin I, cardiac 3; Cardiac troponin I]
products gene name :
[Tnni3]
other gene names :
[Tnni3; Tnni3; Tn1; cTnI]
uniprot entry name :
TNNI3_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[2-211aa; Full Length of Mature Protein]
sequence :
ADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKS
KISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLRT
RCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAK
VTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQ
ALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNI
DALSGMEGRKKKFEG
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
image1 heading :
SDS-Page
other info1 :
Species: Mus musculus (Mouse)
other info2 :
Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
products categories :
Signal Transduction
products description :
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
ncbi acc num :
NP_033432.1
ncbi gb acc num :
NM_009406.3
ncbi mol weight :
24,259 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908268); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Cardiac Muscle Contraction Pathway (93345); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121495); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114298); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Muscle Contraction Pathway (927058); Striated Muscle Contraction Pathway (927059)
uniprot summary :
TNNI3: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1. Belongs to the troponin I family. Protein type: Motility/polarity/chemotaxis; Actin-binding; Motor. Cellular Component: sarcomere; troponin complex; myofibril; contractile fiber; cell; cytoplasm. Molecular Function: troponin T binding; troponin C binding; protein domain specific binding; metal ion binding; calcium channel inhibitor activity; actin binding; protein kinase binding; calcium-dependent protein binding. Biological Process: regulation of smooth muscle contraction; cellular calcium ion homeostasis; striated muscle contraction; heart contraction; regulation of muscle contraction; heart development; regulation of systemic arterial blood pressure by ischemic conditions; ventricular cardiac muscle morphogenesis; vasculogenesis; negative regulation of ATPase activity; cardiac muscle contraction