product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Multidrug resistance-associated protein 1 (ABCC1), partial
catalog :
MBS1160885
quantity :
1 mg (E-Coli)
price :
1375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1160885
products type :
Recombinant Protein
products full name :
Recombinant Human Multidrug resistance-associated protein 1 (ABCC1), partial
products short name :
Multidrug resistance-associated protein 1 (ABCC1), partial
products name syn :
Recombinant Multidrug resistance-associated protein 1 (ABCC1), partial; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1 Leukotriene C(4) transporter; LTC4 transporter
other names :
multidrug resistance-associated protein 1; Multidrug resistance-associated protein 1; multidrug resistance-associated protein 1; LTC4 transporter; leukotriene C(4) transporter; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex13 ATP-binding cassette transporter variant ABCC1delta-ex25 ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette sub-family C member 1; Leukotriene C(4) transporter
products gene name syn :
ABCC1; MRP, MRP1
other gene names :
ABCC1; ABCC1; MRP; ABCC; GS-X; MRP1; ABC29; MRP; MRP1; LTC4 transporter
uniprot entry name :
MRP1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Homo sapiens (Human)
ncbi gi num :
134142337
ncbi acc num :
NP_004987.2
ncbi gb acc num :
NM_004996.3
uniprot acc num :
P33527
ncbi mol weight :
171,591 Da
ncbi pathways :
, Pathway (160982); , Pathway (160981); ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (106573); Irinotecan Pathway (198905); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); S1P1 Pathway (137937); Sphingosine 1-phosphate (S1P) Pathway (137931)
ncbi summary :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
uniprot summary :
ABCC1: a multi-pass membrane protein. A multidrug resistance member of the ABC transporter family that confers resistance to anticancer drugs. A multi-pass membrane protein. Exports sphingosine-1-phosphate (S1P), a potent inflammatory mediator, from mast cells during mast cell-mediated immune responses. Nine alternatively spliced human isoforms have been reported. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family. Chromosomal Location of Human Ortholog: 16p13.1. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATPase activity; ATP binding. Biological Process: response to drug; vitamin metabolic process; cobalamin metabolic process; transport; arachidonic acid metabolic process; leukotriene metabolic process; transmembrane transport; water-soluble vitamin metabolic process
size1 :
1 mg (E-Coli)
price1 :
1375 USD
size2 :
1 mg (Yeast)
price2 :
1835
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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