catalog number :
MBS1157837
products type :
Recombinant Protein
products full name :
Recombinant Human Protein-glutamine gamma-glutamyltransferase 6 (TGM6)
products short name :
Protein-glutamine gamma-glutamyltransferase 6 (TGM6)
products name syn :
Protein-glutamine gamma-glutamyltransferase 6; EC=2.3.2.13; Transglutaminase Y; TGY; TGase Y; Transglutaminase-3-like; TGase-3-like; Transglutaminase-6; TG6; TGase-6
other names :
protein-glutamine gamma-glutamyltransferase 6 isoform 2; Protein-glutamine gamma-glutamyltransferase 6; protein-glutamine gamma-glutamyltransferase 6; TGase Y; TGase-6; transglutaminase y; transglutaminase 6; Transglutaminase Y; TGY; TGase Y; Transglutaminase-3-like; TGase-3-like; Transglutaminase-6; TG6; TGase-6
products gene name :
TGM6
products gene name syn :
TGM6; TGM3L
other gene names :
TGM6; TGM6; TG6; TGY; SCA35; TGM3L; dJ734P14.3; TGM3L; TGY; TGase Y; TGase-3-like; TG6; TGase-6
uniprot entry name :
TGM3L_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-706
sequence :
MAGIRVTKVD WQRSRNGAAH HTQEYPCPEL VVRRGQSFSL TLELSRALDC EEILIFTMET GPRASEALHT KAVFQTSELE RGEGWTAARE AQMEKTLTVS LASPPSAVIG RYLLSIRLSS HRKHSNRRLG EFVLLFNPWC AEDDVFLASE EERQEYVLSD SGIIFRGVEK HIRAQGWNYG QFEEDILNIC LSILDRSPGH QNNPATDVSC RHNPIYVTRV ISAMVNSNND RGVVQGQWQG KYGGGTSPLH WRGSVAILQK WLKGRYKPVK YGQCWVFAGV LCTVLRCLGI ATRVVSNFNS AHDTDQNLSV DKYVDSFGRT LEDLTEDSMW NFHVWNESWF ARQDLGPSYN GWQVLDATPQ EESEGVFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI TWLWHEDESR ERVYSNTKKI GRCISTKAVG SDSRVDITDL YKYPEGSRKE RQVYSKAVNR LFGVEASGRR IWIRRAGGRC LWRDDLLEPA TKPSIAGKFK VLEPPMLGHD LRLALCLANL TSRAQRVRVN LSGATILYTR KPVAEILHES HAVRLGPQEE KRIPITISYS KYKEDLTEDK KILLAAMCLV TKGEKLLVEK DITLEDFITI KVLGPAMVGV AVTVEVTVVN PLIERVKDCA LMVEGSGLLQ EQLSIDVPTL EPQERASVQF DITPSKSGPR QLQVDLVSPH FPDIKGFVIV HVATAK
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
TGM6; TGM3L
ncbi acc num :
NP_001241663.1
ncbi gb acc num :
NM_001254734.1
ncbi mol weight :
70,516 Da
ncbi summary :
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
TGM6: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Two alternatively spliced isoforms have been described. Protein type: Transferase; EC 2.3.2.13. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: cytoplasm. Molecular Function: protein-glutamine gamma-glutamyltransferase activity; metal ion binding. Biological Process: peptide cross-linking. Disease: Spinocerebellar Ataxia 35
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)