catalog number :
MBS1144134
products type :
Recombinant Protein
products full name :
Recombinant Rabies virus Nucleoprotein (N)
products short name :
Nucleoprotein (N)
products name syn :
Nucleoprotein; NP; Nucleocapsid protein; Protein N
other names :
Nucleoprotein; Nucleoprotein; Nucleocapsid protein; Protein N
other gene names :
N; NP; Protein N
uniprot entry name :
NCAP_RABVI
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-450
sequence :
MDADKIVFKV NNQVVSLKPE IIVDQYEYKY PAIKDLKKPS ITLGKAPDLN KAYKSVLSGL NAAKLDPDDV CSYLAAAMQF FEGTCPEDWT SYGILIARKG DKITPDSLVE IKRTDVEGNW ALTGGMELTR DPTVPEHASL VGLLLSLYRL SKISGQNTGN YKTNIADRIE QIFETAPFIK IVEHHTLMTT HKMCANWSTI PNFRFLAGTY DMFFSRIEHL YSAIRVGTVV TAYEDCSGLV SFTGFIKQIN LTAREAILYF FHKNFEEEIR RMFEPGQETA VPHSYFIHFR SLGLSGKSPY SSNAVGHVFN LIHFVGCYMG QVRSLNATVI AGCAPHEMSV LGGYLGEEFF GKGTFERRFF RDEKELQEYE TAELTKTDVA LADDGTVNSD DEDYFSGETR SPEAVYSRIM MNGGRLKRSH IRRYVSVSSN HQARPNSFAE FLNKTYSSDS
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rabies virus (strain India) (RABV)
products description :
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it'sown mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)