product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Streptococcus pneumoniae serotype 4 Pneumolysin
catalog :
MBS1141054
quantity :
0.05 mg (Yeast)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1141054
products type :
Recombinant Protein
products full name :
Recombinant Streptococcus pneumoniae serotype 4 Pneumolysin
products short name :
Streptococcus pneumoniae serotype 4 Pneumolysin
products name syn :
Thiol-activated cytolysin
other names :
pneumolysin; Pneumolysin; Thiol-activated cytolysin
products gene name :
ply
other gene names :
ply
uniprot entry name :
TACY_STRPN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-471, Full length
sequence length :
471
sequence :
ANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLP
DEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVD
ETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDP
SNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHS
MEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFK
QIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLV
YISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAP
QTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDL
IQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVE
TKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEV
LTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTG
LAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVE
ND
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
products references :
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D., Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J., Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D., Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D., Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L., McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K., Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A., Morrison D.A., Hollingshead S.K., Fraser C.M.Science 293:498-506(2001)
ncbi gi num :
447207105
ncbi acc num :
WP_001284361.1
ncbi gb acc num :
WP_001284361.1
uniprot acc num :
P0C2J9
ncbi mol weight :
68.73kD
size1 :
0.05 mg (Yeast)
price1 :
190 USD
size2 :
0.05 mg (E-Coli)
price2 :
190
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.2 mg (Yeast)
price4 :
460
size5 :
0.5 mg (Yeast)
price5 :
750
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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