catalog number :
MBS1140246
products type :
Recombinant Protein
products full name :
Recombinant Human Sulfhydryl oxidase 1 (QSOX1)
products short name :
Sulfhydryl oxidase 1 (QSOX1)
products name syn :
Recombinant Sulfhydryl oxidase 1 (QSOX1); Sulfhydryl oxidase 1; hQSOX EC= 1.8.3.2; Quiescin Q6
other names :
sulfhydryl oxidase 1 isoform b; Sulfhydryl oxidase 1; sulfhydryl oxidase 1; hQSOX; quiescin Q6 sulfhydryl oxidase 1; Quiescin Q6
products gene name syn :
QSOX1; QSCN6; UNQ2520/PRO6013
other gene names :
QSOX1; QSOX1; Q6; QSCN6; QSCN6; hQSOX
uniprot entry name :
QSOX1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
81-180
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_001004128.1
ncbi gb acc num :
NM_001004128.2
ncbi mol weight :
82,578 Da
ncbi summary :
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
quiescin Q6: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; Membrane protein, integral; EC 1.8.3.2. Chromosomal Location of Human Ortholog: 1q24. Cellular Component: Golgi apparatus; extracellular space; intercellular bridge; intracellular membrane-bound organelle; integral to Golgi membrane. Molecular Function: protein disulfide isomerase activity; flavin-linked sulfhydryl oxidase activity. Biological Process: protein folding; cell redox homeostasis