product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Lassa virus Nucleoprotein
catalog :
MBS1122803
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1122803
products type :
Recombinant Protein
products full name :
Recombinant Lassa virus Nucleoprotein
products short name :
Lassa virus Nucleoprotein
products name syn :
Nucleocapsid protein; Protein N
other names :
nucleoprotein; Nucleoprotein; nucleoprotein; Nucleocapsid protein; Protein N
products gene name :
N
other gene names :
LASVsSgp1; N
uniprot entry name :
NCAP_LASSJ
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-569; Full length
sequence length :
569
sequence :
MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALL
HGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLV
ELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTE
RPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAG
RDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDL
NDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDT
KKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQ
TMDGILKSILKVKKALGMFISDTPGERNPYENILYKICL
SGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNN
SSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDI
EGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKY
SHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIR
KLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCH
MHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLN
TSVLRAVLPRDMVFRTSTPRVVL
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: strain Mouse/Sierra Leone/Josiah/1976)(LASV)
products description :
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation
products references :
Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses." Auperin D.D., McCormick J.B. Virology 168:421-425(1989)
ncbi gi num :
23343510
ncbi acc num :
NP_694869.1
ncbi gb acc num :
NC_004296.1
uniprot acc num :
P13699
ncbi mol weight :
65kD
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.05 mg (Yeast)
price2 :
255
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.2 mg (Yeast)
price4 :
665
size5 :
0.5 mg (E-Coli)
price5 :
750
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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