catalog number :
MBS1120624
products type :
Recombinant Protein
products full name :
Recombinant Rat G-protein coupled estrogen receptor 1 (Gper)
products short name :
G-protein coupled estrogen receptor 1 (Gper)
products name syn :
Recombinant G-protein coupled estrogen receptor 1 (Gper); G-protein coupled estrogen receptor 1; Chemoattractant receptor-like 2 G-protein coupled receptor 30 G-protein coupled receptor 41 Membrane estrogen receptor; mER
other names :
G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor 1; mER; chemokine receptor-like 2; membrane estrogen receptor; G protein-coupled receptor 30; G-protein coupled receptor 30; G-protein coupled receptor 41; chemoattractant receptor-like 2; G protein-coupled estrogen receptor 1; Chemoattractant receptor-like 2; G-protein coupled receptor 30; G-protein coupled receptor 41; Membrane estrogen receptor
products gene name syn :
Gper; Cmkrl2, Gpr30, Gpr41
other gene names :
Gper; Gper; GPR41; Gpr30; Cmkrl2; Gpr30; Gpr41; mER
uniprot entry name :
GPER_RAT
sequence positions :
1-375
sequence :
MAATTPAQDVGVEIYLGPVWPAPSNSTPLALNLSLALRE
DAPGNLTGDLSEHQQYVIALFLSCLYTIFLFPIGFVGNI
LILVVNISFREKMTIPDLYFINLAAADLILVADSLIEVF
NLDEQYYDIAVLCTFMSLFLQINMYSSVFFLTWMSFDRY
LALAKAMRCGLFRTKHHARLSCGLIWMASVSATLVPFTA
VHLRHTEEACFCFADVREVQWLEVTLGFIVPFAIIGLCY
SLIVRALIRAHRHRGLRPRRQKALRMIFAVVLVFFICWL
PENVFISVHLLQWAQPGDTPCKQSFRHAYPLTGHIVNLA
AFSNSCLSPLIYSFLGETFRDKLRLYVAQKTSLPALNRF
CHATLKAVIPDSTEQSDVKFSSAV
form :
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Rattus norvegicus (Rat)
other info2 :
Storage Buffer: PBS pH 7.4, 50% glycerol
ncbi acc num :
NP_598257.1
ncbi gb acc num :
NM_133573.1
ncbi mol weight :
42,260 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 574224!!G Alpha (i) Signalling Events Pathway 574252!!GPCR Downstream Signaling Pathway 574250!!GPCR Ligand Binding Pathway 574223!!GPCRs, Class A Rhodopsin-like Pathway 198500!!Peptide Ligand-binding Receptors Pathway 574225!!Signal Transduction Pathway 574116!!Signaling By GPCR Pathway 574222!!Estrogen Signalling Pathway 219761
ncbi summary :
an orphan G protein-coupled receptor found in lung [RGD, Feb 2006]
uniprot summary :
Function: Receptor for estrogen . By similarity. Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein . By similarity. Golgi apparatus membrane; Multi-pass membrane protein. Note: Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor. Ref.2 Ref.3. Tissue specificity: In the paraventricular and supraoptic nuclei of the hypothalamus, expressed in magnocellular neurosecretory cells (MNCs) which secrete oxytocin but not in MNCs which secrete vasopressin (at protein level). Highly expressed in brain and lung, lower expression in heart, skeletal muscle and kidney. Ref.1 Ref.3. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
size :
1 mg (E Coli Derived)