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company name :
MyBioSource
product type :
protein
product name :
Recombinant Bovine coronavirus Hemagglutinin-esterase
catalog :
MBS1120206
quantity :
INQUIRE
price :
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more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1120206
products type :
Recombinant Protein
products full name :
Recombinant Bovine coronavirus Hemagglutinin-esterase
products short name :
Hemagglutinin-esterase
products name syn :
E3 glycoprotein
other names :
Hemagglutinin-esterase; Hemagglutinin-esterase; E3 glycoprotein
products gene name :
HE
other gene names :
HE; HE protein
uniprot entry name :
HEMA_CVBM
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
19-424
sequence length :
424
sequence :
FDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSY
MDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQ
IIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYK
NMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAY
IAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLS
NTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYL
VLPSGNYLAISNELLLTVPTK
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Ses to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.
products references :
Structure and orientation of expressed bovine coronavirus hemagglutinin-esterase protein.Kienzle T.E., Abraham S., Hogue B.G., Brian D.A.J. Virol. 64:1834-1838(1990) Structure and expression of the bovine coronavirus hemagglutinin protein.Kienzle T.E., Abraham S., Hogue B.G., Brian D.A.Adv. Exp. Med. Biol. 276:95-102(1990) Synthesis and processing of the bovine enteric coronavirus haemagglutinin protein.Hogue B.G., Kienzle T.E., Brian D.A.J. Gen. Virol. 70:345-352(1989) Nidovirus sialate-O-acetylesterases evolution and substrate specificity of coronaviral and toroviral receptor-destroying enzymes.Smits S.L., Gerwig G.J., van Vliet A.L., Lissenberg A., Briza P., Kamerling J.P., Vlasak R., de Groot R.J.J. Biol. Chem. 280:6933-6941(2005) Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.Zeng Q., Langereis M.A., van Vliet A.L., Huizinga E.G., de Groot R.J.Proc. Natl. Acad. Sci. U.S.A. 105:9065-9069(2008)
ncbi gi num :
122851
ncbi acc num :
P15776.1
uniprot acc num :
P15776
ncbi mol weight :
47.7kD
size1 :
INQUIRE
price1 :
INQUIRE
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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