product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Escherichia coli (strain K12) LexA repressor
catalog :
MBS1108189
quantity :
0.01 mg (E-Coli)
price :
145 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1108189
products type :
Recombinant Protein
products full name :
Recombinant Escherichia coli (strain K12) LexA repressor
products short name :
LexA repressor
products name syn :
Escherichia coli (strain K12)
other names :
transcriptional repressor of SOS regulon; LexA repressor; transcriptional repressor of SOS regulon
products gene name :
lexA
other gene names :
lexA; lexA; ECK4035; exrA; JW4003; spr; tsl; umuA
uniprot entry name :
LEXA_ECOLI
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-202
sequence length :
202
sequence :
MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRS
PNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPL
VGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSG
MSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVK
RLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGV
IRNGDWL
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Escherichia coli (strain K12)
products categories :
Microbiology
products description :
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment. The SOS response controls an apoptotic-like death (ALD) induced (in the absence of the mazE-mazF toxin-antitoxin module) in response to DNA damaging agents that is mediated by RecA and LexA
products references :
Purified lexA protein is a repressor of the recA and lexA genes." Little J.W., Mount D.W., Yanisch-Perron C.R. Proc. Natl. Acad. Sci. U.S.A. 78:4199-4203(1981)
ncbi gi num :
16131869
ncbi acc num :
NP_418467.1
ncbi gb acc num :
NC_000913.3
uniprot acc num :
P0A7C2
ncbi mol weight :
22,358 Da
ncbi summary :
LexA autocleavage, stimulated by RecA, of the first 84 aa of LexA removes the DNA binding region and is required to activate the SOS response. [More information is available at EcoGene: EG10533]. LexA is a protein that belongs to the LexA family . [More information is available at EcoCyc: EG10533].
size1 :
0.01 mg (E-Coli)
price1 :
145 USD
size2 :
0.05 mg (E-Coli)
price2 :
205
size3 :
0.2 mg (E-Coli)
price3 :
520
size4 :
0.5 mg (E-Coli)
price4 :
850
size5 :
0.05 mg (Baculovirus)
price5 :
950
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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