catalog number :
MBS1098369
products type :
Recombinant Protein
products full name :
Recombinant Bordetella pertussis Serotype 3 fimbrial subunit
products short name :
Serotype 3 fimbrial subunit
other names :
serotype 3 fimbrial subunit; Serotype 3 fimbrial subunit; serotype 3 fimbrial subunit
products gene name :
fim3
other gene names :
fim3; fim3
uniprot entry name :
FM3_BORPE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
26-204
sequence :
NDGTIVITGSISDQTCVIEEPSTLNHIKVVQLPKISKNA
LRNDGDTAGATPFDIKLKECPQALGALKLYFEPGITTNY
DTGDLIAYKQTYNASGNGNLSTVSSATKAKGVEFRLANL
NGQHIRMGTDKTTQAAQTFTGKVTNGSKSYTLRYLASYV
KKPKEDVDAAQITSYVGFSVVYP
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B. pertussis are prime candidates for being involved in this process.
products references :
Structure of the Bordetella pertussis gene coding for the serotype 3 fimbrial subunit.Mooi F.R., Ter Avest A., van der Heide H.G.J.FEMS Microbiol. Lett. 54:327-331(1990)
Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.Nat. Genet. 35:32-40(2003)
ncbi acc num :
NP_880302.1
ncbi gb acc num :
NC_002929.2
ncbi pathways :
Pertussis Pathway (218102); Pertussis Pathway (218099)