catalog number :
MBS107453
products type :
ELISA Kit
products full name :
Bovine Estrone Sulfate ELISA Kit
products short name :
[Estrone Sulfate]
other names :
[estrogen sulfotransferase; Estrogen sulfotransferase; estrogen sulfotransferase; sulfotransferase 1E1; estrone sulfotransferase; sulfotransferase, estrogen-preferring; sulfotransferase family 1E, estrogen-preferring, member 1; EST-1; Sulfotransferase 1E1; ST1E1; Sulfotransferase, estrogen-preferring]
products gene name :
[E1S]
other gene names :
[SULT1E1; SULT1E1; EST; STE; EST-1; ST1E1; STE; ST1E1]
uniprot entry name :
ST1E1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 1.56 ng/ml - 50 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of E1S (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005411.1
ncbi gb acc num :
NM_005420.2
ncbi mol weight :
35,126 Da
ncbi pathways :
Biological Oxidations Pathway (105698); Cytosolic Sulfonation Of Small Molecules Pathway (105724); Estrogen Metabolism Pathway (198898); Metabolism Pathway (477135); Phase II Conjugation Pathway (105721); Steroid Hormone Biosynthesis Pathway (82940); Steroid Hormone Biosynthesis Pathway (301); Sulfation Biotransformation Reaction Pathway (198899); Tamoxifen Metabolism Pathway (198804); Metapathway Biotransformation (198837)
ncbi summary :
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. [provided by RefSeq, Jul 2008]
uniprot summary :
SULT1E1: Sulfotransferase that utilizes 3 -phospho-5 -adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Belongs to the sulfotransferase 1 family. Protein type: Energy Metabolism - sulfur; Transferase; Lipid Metabolism - androgen and estrogen; EC 2.8.2.4. Chromosomal Location of Human Ortholog: 4q13.1. Cellular Component: cytosol. Molecular Function: steroid sulfotransferase activity; estrone sulfotransferase activity; flavonol 3-sulfotransferase activity; steroid binding. Biological Process: steroid metabolic process; estrogen metabolic process; xenobiotic metabolic process; sulfation; female pregnancy; 3 -phosphoadenosine 5 -phosphosulfate metabolic process
size4 :
10x96-Strip-Wells