product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Cavy Microtubule Associated Protein RP/EB Family, Member 1 ELISA Kit
catalog :
MBS107444
quantity :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS107444
products type :
ELISA Kit
products full name :
Cavy Microtubule Associated Protein RP/EB Family, Member 1 ELISA Kit
products short name :
Microtubule Associated Protein RP/EB Family, Member 1
other names :
microtubule-associated protein RP/EB family member 2 isoform 1; Microtubule-associated protein RP/EB family member 2; microtubule-associated protein RP/EB family member 2; end-binding protein 2; APC-binding protein EB1; APC-binding protein EB2; T-cell activation protein, EB1 family; microtubule-associated protein, RP/EB family, member 2; APC-binding protein EB2; End-binding protein 2
products gene name :
MAPRE1
other gene names :
MAPRE2; MAPRE2; EB1; EB2; RP1; RP1; EB2
uniprot entry name :
MARE2_HUMAN
reactivity :
Cavy
sequence length :
327
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
10346135
ncbi acc num :
NP_055083.1
ncbi gb acc num :
NM_014268.3
uniprot acc num :
Q15555
ncbi mol weight :
37,031 Da
ncbi summary :
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
uniprot summary :
Function: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration . By similarity. Subunit structure: Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin. Ref.1 Ref.9 Ref.10. Subcellular location: Cytoplasm cytoskeleton. Note: Associated with the microtubule network. Accumulates at the plus end of microtubules. Ref.9. Tissue specificity: Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. Ref.1. Domain: Composed of two functionally independent domains. The N-terminal domain forms a hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1. Sequence similarities: Belongs to the MAPRE family.Contains 1 CH (calponin-homology) domain.Contains 1 EB1 C-terminal domain. Sequence caution: The sequence BAA83375.1 differs from that shown. Reason: Erroneous initiation.
size :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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