catalog number :
MBS106385
products type :
ELISA Kit
products full name :
Rat Integrin Alpha 3 ELISA Kit
products short name :
[Integrin Alpha 3]
other names :
[integrin alpha-3 isoform a; Integrin alpha-3; integrin alpha-3; FRP-2; galactoprotein B3; VLA-3 subunit alpha; CD49 antigen-like family member C; antigen identified by monoclonal antibody J143; very late activation protein 3 receptor, alpha-3 subunit; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha]
products gene name :
[ITGalpha3]
other gene names :
[ITGA3; ITGA3; VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; MSK18; GAPB3]
uniprot entry name :
ITA3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ITGA3 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002195.1
ncbi gb acc num :
NM_002204.2
ncbi mol weight :
116,612 Da
ncbi pathways :
Arf6 Trafficking Events Pathway (137954); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Basigin Interactions Pathway (106065); CXCR4-mediated Signaling Events Pathway (137910); Cell Surface Interactions At The Vascular Wall Pathway (106062); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); ECM-receptor Interaction Pathway (83068)
ncbi summary :
The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
uniprot summary :
ITGA3: an integral membrane protein that heterodimerizes with a beta chain, forming a receptor for many extracellular-matrix proteins including fibronectin, laminin, collagen, epiligrin and thrombospondin. Undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1. Two alternatively spliced isoforms have been described. Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 17q21.33. Cellular Component: filopodium membrane; cell surface; growth cone; focal adhesion; perinuclear region of cytoplasm; basolateral plasma membrane; plasma membrane; excitatory synapse; integrin complex; receptor complex; external side of plasma membrane. Molecular Function: collagen binding; integrin binding; protein domain specific binding; protein binding; protease binding; protein heterodimerization activity; fibronectin binding; metal ion binding; laminin binding; glycoprotein binding. Biological Process: response to drug; skin development; integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; maternal process involved in pregnancy; cell-matrix adhesion; heart development; regulation of BMP signaling pathway; neuron migration; regulation of Wnt receptor signaling pathway; mesodermal cell differentiation; memory; regulation of transforming growth factor beta receptor signaling pathway; negative regulation of Rho protein signal transduction; blood coagulation; leukocyte migration; negative regulation of cell projection organization and biogenesis; lung development. Disease: Interstitial Lung Disease, Nephrotic Syndrome, And Epidermolysis Bullosa, Congenital
size4 :
10x96-Strip-Wells