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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Caspase-12 (Casp12), partial
catalog :
MBS1061116
quantity :
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price :
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more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1061116
products type :
Recombinant Protein
products full name :
Recombinant Mouse Caspase-12 (Casp12), partial
products short name :
Caspase-12 (Casp12), partial
products name syn :
Caspase-12; CASP-12; EC=3.4.22.-
other names :
caspase-12; Caspase-12; caspase-12; CASP-12; caspase 12
products gene name :
Casp12
other gene names :
Casp12; Casp12; CASP-12
uniprot entry name :
CASPC_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
products description :
Involved in the activation cascade of caspases responsible for apoptosis execution .
ncbi gi num :
157951684
ncbi acc num :
NP_033938.3
ncbi gb acc num :
NM_009808.4
uniprot acc num :
O08736
ncbi mol weight :
47,854 Da
ncbi pathways :
Alzheimer's Disease Pathway (83294); Alzheimer's Disease Pathway (509); Amyotrophic Lateral Sclerosis (ALS) Pathway (83296); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (83257); Apoptosis Pathway (470); Apoptosis Signaling Pathway (522973); Hepatitis B Pathway (694729); Prion Diseases Pathway (101157); Prion Diseases Pathway (100065)
uniprot summary :
CASP12: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis. Belongs to the peptidase C14A family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Protease; EC 3.4.22.-. Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; intracellular; cytosol; nucleus. Molecular Function: peptidase activity; protein binding; protease binding; hydrolase activity; endopeptidase activity; cysteine-type peptidase activity. Biological Process: regulation of apoptosis; protein autoprocessing; positive regulation of apoptosis; apoptosis; unfolded protein response; positive regulation of caspase activity; proteolysis
size1 :
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price1 :
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more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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