catalog number :
MBS105942
products type :
ELISA Kit
products full name :
Camel Lactoferrin ELISA Kit
products short name :
[Lactoferrin]
other names :
[lactoferrin; Lactotransferrin; lactotransferrin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; lactotransferrin; Growth-inhibiting protein 12; Talalactoferrin]
products gene name :
[LF]
other gene names :
[LTF; LTF; LF; HLF2; GIG12; GIG12; LF; Lactoferrin; Lfcin-H]
uniprot entry name :
TRFL_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Bovine Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2ug/ml-1000ug/ml. Sensitivity: 5.0ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of LF (hereafter termed "analyte") in undiluted original Bovine body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAB57795.1
ncbi mol weight :
78,182 Da
ncbi pathways :
Amyloids Pathway (366238); Disease Pathway (530764); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Mtb Iron Assimilation By Chelation Pathway (645273); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); Response Of Mtb To Phagocytosis Pathway (645269)
ncbi summary :
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
uniprot summary :
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: EC 3.4.21.-; Secreted; Protease; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule. Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; DNA binding; ferric iron binding; iron ion binding; serine-type endopeptidase activity. Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; retinal homeostasis; positive regulation of osteoblast differentiation; innate immune response in mucosa; negative regulation of viral genome replication; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of ATPase activity; iron assimilation by chelation and transport; negative regulation of viral reproduction; negative regulation of apoptosis
size4 :
10x96-Strip-Wells