product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Pasteurella haemolytica Leukotoxin(lktA)
catalog :
MBS1052036
quantity :
0.05 mg (Yeast)
price :
185 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1052036
products type :
Recombinant Protein
products full name :
Recombinant Pasteurella haemolytica Leukotoxin(lktA)
products short name :
Haemolytica Leukotoxin
other names :
Leukotoxin; Leukotoxin
products gene name :
lktA
other gene names :
lktA; Lkt
uniprot entry name :
LKA7B_MANHA
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
715-953
sequence length :
953
sequence :
IGTSHNDIFKGSKFNDAFNGGDGVDTIDGNDGNDRLFGG
KGDDIIDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRQGD
GNDSITESEGNDKLSFSDSNLKDLTFEKVNHHLVITNTK
QEKVTIQNWFREAEFAKTIQNYVATRDDKIEEIIGQNGE
RITSKQVDELIEKGNGKIAQSELTKVVDNYQLLKYSRDA
SNSLDKLISSASAFTSSNDSRNVLASPTSMLDPSLSSIQ
FARAA
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca2+ and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak holytic activity.
products references :
Sequence diversity and molecular evolution of the leukotoxin (lktA) gene in bovine and ovine strains of Mannheimia (Pasteurella) haemolytica.Davies R.L., Whittam T.S., Selander R.K.J. Bacteriol. 183:1394-1404(2001)
ncbi gi num :
73621161
ncbi acc num :
P0C085.1
uniprot acc num :
P0C085
ncbi mol weight :
53.3kD
size1 :
0.05 mg (Yeast)
price1 :
185 USD
size2 :
0.2 mg (Yeast)
price2 :
420
size3 :
0.5 mg (Yeast)
price3 :
680
size4 :
1 mg (Yeast)
price4 :
1070
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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