product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
catalog :
MBS1051143
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1051143
products type :
Recombinant Protein
products full name :
Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
products short name :
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
other names :
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19kDa interacting protein 3-like; Adenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; NIP3-like protein X; NIP3L
products gene name :
BNIP3L
other gene names :
BNIP3L; BNIP3L; NIX; BNIP3a; BNIP3A; BNIP3H; NIX; NIP3L
uniprot entry name :
BNI3L_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-219
sequence length :
219
sequence :
MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVEL
PMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDA
QHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHS
SQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEF
HFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFL
SHVLALGLGIYIGKRLSTPSASTY
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Cancer
ncbi gi num :
4757860
ncbi acc num :
NP_004322.1
ncbi gb acc num :
NM_004331.2
uniprot acc num :
O60238
ncbi mol weight :
25.93kD
ncbi pathways :
Apoptosis Pathway (198797); Direct P53 Effectors Pathway (137939)
ncbi summary :
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
uniprot summary :
BNIP3L: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. May function as a tumor suppressor. Self-associates. Interacts with BNIP3 and STEAP3. Interacts with SPATA18/MIEAP. Interacts with human adenovirus-2 E1B 19 kDa protein. Belongs to the NIP3 family. Protein type: Endoplasmic reticulum; Membrane protein, integral; Mitochondrial; Nuclear envelope; Apoptosis. Chromosomal Location of Human Ortholog: 8p21. Cellular Component: endoplasmic reticulum; integral to membrane; intrinsic to membrane; mitochondrial outer membrane; mitochondrion; nuclear envelope. Molecular Function: identical protein binding; lamin binding; protein binding; protein heterodimerization activity; protein homodimerization activity. Biological Process: defense response to virus; negative regulation of apoptosis; positive regulation of apoptosis; positive regulation of macroautophagy; viral reproduction
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.2 mg (E-Coli)
price2 :
460
size3 :
0.5 mg (E-Coli)
price3 :
750
size4 :
1 mg (E-Coli)
price4 :
1180
size5 :
1 mg (Yeast)
price5 :
1835
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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