Horse Bcl2 Like Protein 11 ELISA Kit | MyBioSource MBS104969 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Horse Bcl2 Like Protein 11 ELISA Kit

catalog :

MBS104969

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS104969

products type :

ELISA Kit

products full name :

Horse Bcl2 Like Protein 11 ELISA Kit

products short name :

[Bcl2 Like Protein 11]

other names :

[bcl-2-like protein 11 isoform 18; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death]

products gene name :

[BCL2L11]

other gene names :

[BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11]

uniprot entry name :

B2L11_HUMAN

reactivity :

Horse

sequence length :

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BCL2L11 (hereafter termed "analyte") in undiluted original Horse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

323362973

ncbi acc num :

NP_001191042.1

ncbi gb acc num :

NM_001204113.1

uniprot acc num :

O43521

ncbi mol weight :

22,171 Da

ncbi pathways :

Activation Of BH3-only Proteins Pathway (105658); Activation Of BIM And Translocation To Mitochondria Pathway (105662); Apoptosis Pathway (198797); Apoptosis Pathway (105648); Apoptosis Modulation And Signaling Pathway (198822); B Cell Receptor Signaling Pathway (198909); BDNF Signaling Pathway (712093); BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway (105664); Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); DNA Damage Response (only ATM Dependent) Pathway (198827)

ncbi summary :

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]

uniprot summary :

BIM: a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis. Transgenic studies in the mouse suggested that this protein functions as an essential initiator of the apoptosis in thymocyte-negative selection. Nineteen alternatively spliced transcript variants of this gene have been reported. Protein type: Apoptosis. Chromosomal Location of Human Ortholog: 2q13. Cellular Component: microtubule; mitochondrial outer membrane; extrinsic to membrane; endomembrane system; cytosol. Molecular Function: protein binding; microtubule binding. Biological Process: nerve growth factor receptor signaling pathway; apoptosis; positive regulation of apoptosis; cell-matrix adhesion; pigmentation during development; myeloid cell homeostasis; positive regulation of caspase activity; B cell apoptosis; ear development; cellular process regulating host cell cycle in response to virus; positive regulation of apoptosis by virus; mammary gland development; B cell homeostasis; positive regulation of neuron apoptosis; T cell homeostasis; kidney development; post-embryonic organ morphogenesis; caspase activation; spleen development; thymus development; positive regulation of protein homooligomerization; in utero embryonic development; male gonad development; positive regulation of cell cycle; lumen formation; regulation of organ growth; odontogenesis of dentine-containing teeth; DNA damage response, signal transduction resulting in induction of apoptosis; regulation of pigmentation during development; spermatogenesis; brain development

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095