product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Escherichia coli (strain K12) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
catalog :
MBS1042433
quantity :
0.01 mg (E-Coli)
price :
115 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1042433
products type :
Recombinant Protein
products full name :
Recombinant Escherichia coli (strain K12) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
products short name :
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
products name syn :
Protein envA; UDP-3-O-acyl-GlcNAc deacetylase
other names :
UDP-3-O-acyl N-acetylglucosamine deacetylase; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; UDP-3-O-acyl N-acetylglucosamine deacetylase; Protein EnvA; UDP-3-O-acyl-GlcNAc deacetylase
products gene name :
lpxC
other gene names :
lpxC; lpxC; asmB; ECK0097; envA; JW0094; asmB; envA
uniprot entry name :
LPXC_ECOLI
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-305
sequence length :
305
sequence :
MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIY
RRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVE
HLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLD
AGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLD
FTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFM
RDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDE
FVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQ
AVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Escherichia coli (strain K12)
products description :
The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal.
products references :
Sequence analysis, transcriptional organization, and insertional mutagenesis of the envA gene of Escherichia coli." Beall B., Lutkenhaus J. J. Bacteriol. 169:5408-5415(1987)
ncbi gi num :
16128089
ncbi acc num :
NP_414638.1
ncbi gb acc num :
NC_000913.3
uniprot acc num :
P0A725
ncbi mol weight :
38.03kD
ncbi pathways :
Lipopolysaccharide Biosynthesis Pathway (1058); Lipopolysaccharide Biosynthesis Pathway (359); Lipopolysaccharide Biosynthesis, KDO2-lipid A Pathway (405193); Lipopolysaccharide Biosynthesis, KDO2-lipid A Pathway (468253); Metabolic Pathways (131985); Lipid IVA Biosynthesis Pathway (54); Lipid IVA Biosynthesis Pathway (138321); Superpathway Of (Kdo)2-lipid A Biosynthesis (52); Superpathway Of (Kdo)2-lipid A Biosynthesis (138319); Superpathway Of Lipopolysaccharide Biosynthesis (98)
ncbi summary :
LpxC regulated degradation is facilitated by FtsH. [More information is available at EcoGene: EG10265]. UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) catalyzes the second reaction and the first committed step in lipid A biosynthesis. [More information is available at EcoCyc: EG10265].
size1 :
0.01 mg (E-Coli)
price1 :
115 USD
size2 :
0.05 mg (E-Coli)
price2 :
185
size3 :
0.2 mg (E-Coli)
price3 :
420
size4 :
0.5 mg (E-Coli)
price4 :
680
size5 :
1 mg (E-Coli)
price5 :
1070
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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