catalog number :
MBS1017200
products type :
Recombinant Protein
products full name :
Recombinant Rat Regenerating islet-derived protein 3-beta
products short name :
Regenerating islet-derived protein 3-beta
products name syn :
Pancreatitis-associated protein 1; Peptide 23; REG-2; Regenerating islet-derived protein III-beta; Reg III-beta
other names :
regenerating islet-derived protein 3-beta; Regenerating islet-derived protein 3-beta; regenerating islet-derived protein 3-beta; regenerating islet-derived 3 beta; Pancreatitis-associated protein 1; Peptide 23; REG-2; Regenerating islet-derived protein III-beta; Reg III-beta
products gene name :
Reg3b
other gene names :
Reg3b; Reg3b; Pap; Pap1; Pap; Pap1; Reg2; REG-3-beta; Reg III-beta
uniprot entry name :
REG3B_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
27-175
sequence :
EDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAE
LACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWI
GLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDR
GFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Bactericidal C-type lectin which acts against several intestinal Gram-positive bacteria and Gram-negative bacteria. Lacks antibacterial activity against S. typhimurium. May play a role in protection against infection with S. enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues.
products references :
Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis.Iovanna J., Orelle B., Keim V., Dagorn J.-C.J. Biol. Chem. 266:24664-24669(1991)
PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine.Iovanna J.L., Keim V., Bosshard A., Orelle B., Frigerio J.-M., Dusetti N., Dagorn J.-C.Am. J. Physiol. 265:G611-G618(1993)
Structural organization of the gene encoding the rat pancreatitis-associated protein. Analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition domain-containing genes.Dusetti N.J., Frigerio J.-M., Keim V., Dagorn J.-C., Iovanna J.J. Biol. Chem. 268:14470-14475(1993)
Sequence of a cDNA clone encoding a rat Reg-2 protein.Kamimura T., West C., Beutler E.Gene 118:299-300(1992)
Molecular cloning and expression of peptide 23, a growth hormone-releasing hormone-inducible pituitary protein.Katsumata N., Chakraborty C., Myal Y., Schroedter I.C., Murphy L.J., Shiu R.P., Friesen H.G.Endocrinology 136:1332-1339(1995)
ncbi acc num :
NP_445741.1
ncbi gb acc num :
NM_053289.1
ncbi mol weight :
20.72kD
ncbi summary :
lectin-related secretory protein; may be involved in stress response to control bacterial proliferation during acute pancreatitis [RGD, Feb 2006]
size4 :
0.05 mg (Baculovirus)
size5 :
0.05 mg (Mammalian-Cell)