product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Naja atra (Chinese cobra) Cytotoxin 4
catalog :
MBS1014748
quantity :
0.01 mg (E-Coli)
price :
110 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1014748
products type :
Recombinant Protein
products full name :
Recombinant Naja atra (Chinese cobra) Cytotoxin 4
products short name :
Cytotoxin 4
products name syn :
Cardiotoxin A4; CTX A4; Cardiotoxin analog IV
other names :
Cytotoxin 4; Cytotoxin 4; Cardiotoxin A4
products gene name :
CTX IV
other gene names :
CTX IV; CTX IV
uniprot entry name :
3SA4_NAJAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
22-81
sequence length :
81
sequence :
RKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCI
DVCPKNSALVKYVCCNTDRCN
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Naja atra (Chinese cobra)
products description :
Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation.
products references :
Genomic structures of cardiotoxin 4 and cobrotoxin from Naja naja atra (Taiwan cobra)." Chang L.-S., Lin J., Chou Y.-C., Hong E. Biochem. Biophys. Res. Commun. 239:756-762(1997)
ncbi gi num :
2851458
ncbi acc num :
P01443.2
uniprot acc num :
P01443
ncbi mol weight :
22.79kD
size1 :
0.01 mg (E-Coli)
price1 :
110 USD
size2 :
0.05 mg (E-Coli)
price2 :
190
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.5 mg (E-Coli)
price4 :
750
size5 :
0.05 mg (Baculovirus)
price5 :
785
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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