Fish Bisphenol A ELISA Kit | MyBioSource MBS099018 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Fish Bisphenol A ELISA Kit

catalog :

MBS099018

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS099018

products type :

ELISA Kit

products full name :

Fish Bisphenol A ELISA Kit

products short name :

[Bisphenol A]

other names :

[bisphenol A receptor ERRgamma2; Estrogen-related receptor gamma; estrogen-related receptor gamma; ERR gamma-2; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3; estrogen-related receptor gamma; ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3]

products gene name :

[BPA]

other gene names :

[ESRRG; ESRRG; ERR3; NR3B3; ERRgamma; ERR3; ERRG2; KIAA0832; NR3B3]

uniprot entry name :

ERR3_HUMAN

reactivity :

Fish

sequence length :

435

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 6.25 ug/ml - 200 ug/ml. Sensitivity: 1.0 ug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BPA (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

226000901

ncbi acc num :

BAH36764.1

uniprot acc num :

P62508

ncbi mol weight :

51,306 Da

ncbi pathways :

Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Nuclear Receptor Transcription Pathway (105979)

ncbi summary :

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011]

uniprot summary :

ERR3: Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Belongs to the nuclear hormone receptor family. NR3 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; DNA-binding; Nuclear receptor. Chromosomal Location of Human Ortholog: 1q41. Cellular Component: nucleoplasm. Molecular Function: protein binding; AF-2 domain binding; zinc ion binding; steroid hormone receptor activity; retinoic acid receptor activity; steroid binding. Biological Process: retinoic acid receptor signaling pathway; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; gene expression; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage