Rat Diacylglycerol-O-Acyltransferase Homolog 1 ELISA Kit | MyBioSource MBS098711 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Diacylglycerol-O-Acyltransferase Homolog 1 ELISA Kit

catalog :

MBS098711

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS098711

products type :

ELISA Kit

products full name :

Rat Diacylglycerol-O-Acyltransferase Homolog 1 ELISA Kit

products short name :

[Diacylglycerol-O-Acyltransferase Homolog 1]

other names :

[diacylglycerol O-acyltransferase 2 isoform 1; Diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase 2; diglyceride acyltransferase 2; retinol O-fatty-acyltransferase; acyl-CoA retinol O-fatty-acyltransferase; diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; diacylglycerol O-acyltransferase 2; Acyl-CoA retinol O-fatty-acyltransferase (EC:2.3.1.76); ARAT; Retinol O-fatty-acyltransferase; Diglyceride acyltransferase 2]

products gene name :

[DGAT1]

other gene names :

[DGAT2; DGAT2; ARAT; HMFN1045; GS1999FULL; ARAT; Retinol O-fatty-acyltransferase]

uniprot entry name :

DGAT2_HUMAN

reactivity :

Rat

sequence length :

388

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DGAT1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

26024197

ncbi acc num :

NP_115953.2

ncbi gb acc num :

NM_032564.4

uniprot acc num :

Q96PD7

ncbi mol weight :

43,831 Da

ncbi pathways :

Acyl Chain Remodeling Of DAG And TAG Pathway (645315); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Biosynthesis Pathway (645313); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Phospholipid Metabolism Pathway (645312)

ncbi summary :

This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

uniprot summary :

DGAT2: Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Belongs to the diacylglycerol acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Lipid Metabolism - glycerolipid; Transferase; Membrane protein, multi-pass; EC 2.3.1.76; Cofactor and Vitamin Metabolism - retinol; EC 2.3.1.20. Chromosomal Location of Human Ortholog: 11q13.5. Cellular Component: endoplasmic reticulum membrane; mitochondrion; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; integral to endoplasmic reticulum membrane; lipid particle. Molecular Function: 2-acylglycerol O-acyltransferase activity; protein homodimerization activity; retinol O-fatty-acyltransferase activity; diacylglycerol O-acyltransferase activity. Biological Process: cholesterol homeostasis; sequestering of lipid; retinol metabolic process; glycerol metabolic process; phospholipid metabolic process; fatty acid homeostasis; glycerophospholipid biosynthetic process; triacylglycerol biosynthetic process; diacylglycerol metabolic process; cellular lipid metabolic process

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage