Mouse Lipase, Bile Salt Dependent ELISA Kit | MyBioSource MBS098208 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Lipase, Bile Salt Dependent ELISA Kit

catalog :

MBS098208

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS098208

products type :

ELISA Kit

products full name :

Mouse Lipase, Bile Salt Dependent ELISA Kit

products short name :

[Lipase, Bile Salt Dependent]

other names :

[bile salt-activated lipase; Bile salt-activated lipase; bile salt-activated lipase; bucelipase; sterol esterase; cholesterol esterase; carboxyl ester hydrolase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; bile salt-dependent lipase, oncofetal isoform; carboxyl ester lipase (bile salt-stimulated lipase); carboxyl ester lipase; Bile salt-stimulated lipase; BSSL; Bucelipase; Carboxyl ester lipase; Cholesterol esterase; Pancreatic lysophospholipase; Sterol esterase]

products gene name :

[BSDL]

other gene names :

[CEL; CEL; BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8; BAL; BAL; BSSL]

uniprot entry name :

CEL_HUMAN

reactivity :

Mouse

sequence length :

756

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BSDL (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

148536848

ncbi acc num :

NP_001798.2

ncbi gb acc num :

NM_001807.4

uniprot acc num :

P19835

ncbi mol weight :

79,322 Da

ncbi pathways :

Acylglycerol Degradation Pathway (413388); Acylglycerol Degradation Pathway (468272); Digestion Of Dietary Lipid Pathway (106112); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Lipid Digestion, Mobilization, And Transport Pathway (106111); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

ncbi summary :

The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]

uniprot summary :

CEL: Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides. Defects in CEL are a cause of maturity-onset diabetes of the young type 8 with exocrine dysfunction (MODY8); also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Lipid Metabolism - steroid biosynthesis; EC 3.1.1.13; Lipid Metabolism - glycerolipid; Lipase; EC 3.1.1.3. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: extracellular space; cytoplasm; extracellular region. Molecular Function: sterol esterase activity; heparin binding; triacylglycerol lipase activity; protein binding; hydrolase activity; acylglycerol lipase activity; catalytic activity. Biological Process: intestinal lipid catabolic process; triacylglycerol metabolic process; cholesterol absorption; fatty acid catabolic process; lipid metabolic process; pancreatic juice secretion; protein amino acid esterification; cholesterol catabolic process; lipid digestion. Disease: Maturity-onset Diabetes Of The Young, Type 8, With Exocrine Dysfunction

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage