catalog number :
MBS097298
products type :
ELISA Kit
products full name :
Rat Interleukin 28A ELISA Kit
products short name :
[Interleukin 28A]
other names :
[interferon lambda-2; Interferon lambda-2; interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2); interferon, lambda 2; Cytokine Zcyto20; Interleukin-28A]
products gene name :
[IL28A]
other gene names :
[IFNL2; IFNL2; IL28A; IL-28A; IL28A; ZCYTO20; IFN-lambda-2; IL-28A]
uniprot entry name :
IFNL2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 15.6 pg/ml - 500 pg/ml. Sensitivity: 2.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IL28A (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_742150.1
ncbi gb acc num :
NM_172138.1
ncbi mol weight :
22,288 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Type III Interferon Signaling Pathway (755437)
ncbi summary :
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
uniprot summary :
IL28A: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family. Protein type: Cytokine; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.13. Cellular Component: extracellular space. Molecular Function: cytokine activity. Biological Process: positive regulation of immune response; mucosal immune response; JAK-STAT cascade; defense response to virus
size4 :
10x96-Strip-Wells