catalog number :
MBS096621
products type :
ELISA Kit
products full name :
Human Androsterone ELISA Kit
products short name :
[Androsterone]
other names :
[Aldo-keto reductase family 1 member C21; Aldo-keto reductase family 1 member C21; aldo-keto reductase family 1 member C21; DD1; DD3; 17-alpha-HSD; dihydrodiol dehydrogenase type 1; dihydrodiol dehydrogenase type 3; 3-alpha-hydroxysteroid dehydrogenase; 17-alpha-hydroxysteroid dehydrogenase; 3(17)alpha-hydroxysteroid dehydrogenase; 3(or 17)-alpha-hydroxysteroid dehydrogenase; aldo-keto reductase family 1, member C21; 17-alpha-hydroxysteroid dehydrogenase; 17-alpha-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase (EC:1.1.1.209); 3-alpha-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase type 1; DD1; Dihydrodiol dehydrogenase type 3; DD3]
products gene name :
[ADT]
other gene names :
[Akr1c21; Akr1c21; AI315367; 9430025F20Rik; 17-alpha-HSD; DD1; DD3]
uniprot entry name :
AK1CL_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 nmol/L - 20 nmol/L. Sensitivity: 0.1 nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ADT (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi mol weight :
36,877 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (970916); Bile Acid And Bile Salt Metabolism Pathway (1001055); Disease Pathway (970606); Diseases Associated With Visual Transduction Pathway (971454); Glucocorticoid Mineralcorticoid Metabolism Pathway (198290); Metabolism Pathway (971233); Metabolism Of Lipids And Lipoproteins Pathway (970615); Retinoid Metabolism And Transport Pathway (1000673); Signal Transduction Pathway (970540); Synthesis Of Prostaglandins (PG) And Thromboxanes (TX) Pathway (970914)
uniprot summary :
AKR1C2: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Defects in AKR1C2 are a cause of 46,XY sex reversal type 8 (SRXY8). A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Belongs to the aldo/keto reductase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; EC 1.3.1.20; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.357. Cellular Component: cytoplasm; cytosol. Molecular Function: mevaldate reductase activity; bile acid binding; oxidoreductase activity; C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; phenanthrene 9,10-monooxygenase activity; 3(or 17)-alpha-hydroxysteroid dehydrogenase activity; (R)-2-hydroxyisocaproate dehydrogenase activity; steroid dehydrogenase activity; carboxylic acid binding; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; D-arabinitol dehydrogenase (NADP+) activity; aldehyde reductase activity; acetoin dehydrogenase activity; gluconate dehydrogenase activity; (R)-2-hydroxyglutarate dehydrogenase activity; phenylcoumaran benzylic ether reductase activity; aldo-keto reductase activity; arabinose reductase activity; isocitrate dehydrogenase activity; epoxide dehydrogenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ketosteroid monooxygenase activity; 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity; 3-ketoglucose-reductase activity; steroid dehydrogenase activity, acting on the CH-CH group of donors; 2-hydroxytetrahydrofuran dehydrogenase activity; 5-exo-hydroxycamphor dehydrogenase activity; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; xylose reductase activity. Biological Process: steroid metabolic process; lipid metabolic process; steroid biosynthetic process
size4 :
10x96-Strip-Wells