Human Mannose Associated Serine Protease 2 ELISA Kit | MyBioSource MBS094319 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Mannose Associated Serine Protease 2 ELISA Kit

catalog :

MBS094319

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS094319

products type :

ELISA Kit

products full name :

Human Mannose Associated Serine Protease 2 ELISA Kit

products short name :

[Mannose Associated Serine Protease 2]

other names :

[mannan-binding lectin serine protease 2 isoform 1 preproprotein; Mannan-binding lectin serine protease 2; mannan-binding lectin serine protease 2; small MBL-associated protein; MBL-associated serine protease 2; MBL-associated plasma protein of 19 kD; mannan-binding lectin serine protease 1 pseudogene 1; mannose-binding protein-associated serine protease 2; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2]

products gene name :

[MASP2]

other gene names :

[MASP2; MASP2; sMAP; MAP19; MASP-2; MASP1P1; MASP-2]

uniprot entry name :

MASP2_HUMAN

reactivity :

Human

sequence length :

686

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2pg/ml-1000pg/ml. Sensitivity: 5.0pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of MAS1 (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

21264363

ncbi acc num :

NP_006601.2

ncbi gb acc num :

NM_006610.3

uniprot acc num :

O00187

ncbi mol weight :

75,702 Da

ncbi pathways :

Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); Ficolins Bind To Repetitive Carbohydrate Structures On The Target Cell Surface Pathway (833818); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Lectin Pathway Of Complement Activation (106408)

ncbi summary :

The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq, Jul 2008]

uniprot summary :

MASP2: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. Defects in MASP2 are the cause of MASP2 deficiency (MASPD). MASPD is a disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Protease; Secreted, signal peptide; EC 3.4.21.104; Secreted. Chromosomal Location of Human Ortholog: 1p36.3-p36.2. Cellular Component: extracellular region. Molecular Function: peptidase activity; protein binding; serine-type endopeptidase activity; complement component C4b binding; calcium ion binding; calcium-dependent protein binding. Biological Process: innate immune response; proteolysis; complement activation, lectin pathway; complement activation, classical pathway; complement activation. Disease: Masp2 Deficiency

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095