catalog number :
MBS090660
products type :
ELISA Kit
products full name :
Fish Calpain 1, Large Subunit ELISA Kit
products short name :
[Calpain 1, Large Subunit]
other names :
[calpain 1, (mu/I) large subunit, isoform CRA_c; Calpain-1 catalytic subunit; calpain-1 catalytic subunit; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein; calpain 1, (mu/I) large subunit; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain]
products gene name :
[CAPN1]
other gene names :
[CAPN1; CAPN1; CANP; muCL; CANP1; CANPL1; muCANP; CANPL1; CANP 1; muCANP]
uniprot entry name :
CAN1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CAPN1 (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
EAW74368.1
ncbi mol weight :
81,890 Da
ncbi summary :
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
uniprot summary :
CAPN1: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Forms a heterodimer with a small (regulatory) subunit (CAPNS1). Ubiquitous. Activated by micromolar concentrations of calcium and inhibited by calpastatin. Belongs to the peptidase C2 family. Protein type: Motility/polarity/chemotaxis; EC 3.4.22.52; Protease. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: focal adhesion; membrane; cytoplasm; plasma membrane; cytosol. Molecular Function: protein binding; calcium-dependent cysteine-type endopeptidase activity; calcium ion binding. Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; receptor catabolic process; positive regulation of cell proliferation; proteolysis
size4 :
10x96-Strip-Wells