catalog number :
MBS088605
products type :
ELISA Kit
products full name :
Duck Chemerin ELISA Kit
products short name :
[Chemerin]
other names :
[chemokine-like receptor 1 isoform a; Chemokine-like receptor 1; chemokine-like receptor 1; chemerin receptor; resolvin E1 receptor; chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; orphan G-protein coupled receptor, Dez; chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ]
products gene name :
[CHE]
other gene names :
[CMKLR1; CMKLR1; DEZ; RVER1; ChemR23; CHEMERINR; CHEMR23; DEZ]
uniprot entry name :
CML1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25pg/ml-200pg/ml. Sensitivity: 1.0pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of CGRP (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001135817.1
ncbi gb acc num :
NM_001142345.1
ncbi mol weight :
42,322 Da
ncbi pathways :
GPCRs, Class A Rhodopsin-like Pathway (198886)
uniprot summary :
CMKLR1: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: 12q24.1. Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane. Molecular Function: G-protein coupled receptor activity; protein binding; chemokine receptor activity; receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of interleukin-12 production; inhibition of NF-kappaB transcription factor; positive regulation of fat cell differentiation; regulation of calcium-mediated signaling; immune response; chemotaxis; skeletal development
size4 :
10x96-Strip-Wells