catalog number :
MBS086049
products type :
ELISA Kit
products full name :
Mouse Carbon Catabolite Repression 4 Like Protein ELISA Kit
products short name :
[Carbon Catabolite Repression 4 Like Protein]
other names :
[CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex subunit 6-like; carbon catabolite repressor protein 4 homolog B; CCR4-NOT transcription complex, subunit 6-like; Carbon catabolite repressor protein 4 homolog B]
products gene name :
[CCRN4L]
other gene names :
[CNOT6L; CNOT6L; CCR4b; CCR4B]
uniprot entry name :
CNO6L_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CCRN4L (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi mol weight :
63,001 Da
ncbi pathways :
Deadenylation Of MRNA Pathway (160994); Deadenylation-dependent MRNA Decay Pathway (160993); Gene Expression Pathway (105937); RNA Degradation Pathway (117291); RNA Degradation Pathway (116127)
uniprot summary :
CNOT6L: Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3 -5 poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the 3 -UTR AU-rich element-mediated mechanism. Involved in deadenylation- dependent degradation of CDKN1B mRNA. Belongs to the CCR4/nocturin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.1.13.4; Hydrolase. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: cytoplasm; nucleus; cytosol; CCR4-NOT complex. Molecular Function: protein binding; poly(A)-specific ribonuclease activity; metal ion binding. Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; gene expression; RNA-mediated gene silencing; mRNA catabolic process, deadenylation-dependent decay
size4 :
10x96-Strip-Wells