Mouse Myosin Heavy Chain 2, Skeletal Muscle, Adult ELISA Kit | MyBioSource MBS084181 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Myosin Heavy Chain 2, Skeletal Muscle, Adult ELISA Kit

catalog :

MBS084181

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS084181

products type :

ELISA Kit

products full name :

Mouse Myosin Heavy Chain 2, Skeletal Muscle, Adult ELISA Kit

products short name :

[Myosin Heavy Chain 2, Skeletal Muscle, Adult]

other names :

[myosin-2; Myosin-2; myosin-2; myosin heavy chain 2; myosin heavy chain 2a; myosin heavy chain IIa; fast 2a myosin heavy chain; type IIA myosin heavy chain; myosin heavy chain, skeletal muscle, adult 2; inclusion body myopathy 3, autosomal dominant; myosin, heavy polypeptide 2, skeletal muscle, adult; myosin, heavy chain 2, skeletal muscle, adult; Myosin heavy chain 2; Myosin heavy chain 2a; MyHC-2a; Myosin heavy chain IIa; MyHC-IIa; Myosin heavy chain, skeletal muscle, adult 2]

products gene name :

[MYH2]

other gene names :

[MYH2; MYH2; IBM3; MYH2A; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa; MYHSA2; MyHC-2a; MyHC-IIa]

uniprot entry name :

MYH2_HUMAN

reactivity :

Mouse

sequence length :

1941

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 1.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MYH2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

153792663

ncbi acc num :

NP_060004.3

ncbi gb acc num :

NM_017534.5

uniprot acc num :

Q9UKX2

ncbi mol weight :

223,044 Da

ncbi pathways :

Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Immune System Pathway (106386); Innate Immune System Pathway (106387); Membrane Trafficking Pathway (106160); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (771579); Tight Junction Pathway (83071); Tight Junction Pathway (482); Translocation Of GLUT4 To The Plasma Membrane Pathway (685554); Amb2 Integrin Signaling Pathway (137945)

ncbi summary :

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]

uniprot summary :

MYH2: Muscle contraction. Required for cytoskeleton organization. Defects in MYH2 are the cause of inclusion body myopathy type 3 (IBM3). Hereditary inclusion body myopathies constitute a group of neuromuscular disorders characterized by slowly progressive distal and proximal weakness and a typical muscle pathology including rimmed vacuoles and filamentous inclusions. IBM3 is a variant of hereditary inclusion body myopathies and is characterized by autosomal dominant myopathy with joint contracture, ophthalmoplegia and rimmed vacuoles. Morphological analysis of muscle biopsies from patients indicate that the type 2A fibers frequently were abnormal, whereas other fiber types appeared normal. Protein type: Motor; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: Golgi apparatus; sarcomere; protein complex; myofibril; contractile ring; muscle myosin complex; intercellular junction; cytosol; A band. Molecular Function: microfilament motor activity; calmodulin binding; protein binding; actin binding; ATP binding. Biological Process: muscle contraction; metabolic process; plasma membrane repair; innate immune response; response to activity; muscle filament sliding. Disease: Inclusion Body Myopathy 3, Autosomal Dominant

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage