ELISA/assay

Mouse Chloride Channel Accessory 1 ELISA Kit

MBS084015

48-Strip-Wells

435 USD

ELISA Kit

Mouse Chloride Channel Accessory 1 ELISA Kit

Chloride Channel Accessory 1

calcium-activated chloride channel regulator 1; Calcium-activated chloride channel regulator 1; calcium-activated chloride channel regulator 1; calcium-dependent chloride channel-1; calcium-activated chloride channel protein 1; CLCA family member 1, chloride channel regulator; calcium-activated chloride channel family member 1; chloride channel, calcium activated, family member 1; chloride channel accessory 1; Calcium-activated chloride channel family member 1; hCLCA1; Calcium-activated chloride channel protein 1

CLCA1

CLCA1; CLCA1; CACC; GOB5; CACC1; CLCRG1; CaCC-1; hCLCA1; hCaCC-1; CACC1; hCLCA1; CaCC-1; hCaCC-1

CLCA1_HUMAN

Mouse

914

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CLCA1 (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.

110611231

NP_001276.2

NM_001285.3

A8K7I4

100,226 Da

Alpha6-Beta4 Integrin Signaling Pathway (198807); Ion Channel Transport Pathway (187193); Olfactory Transduction Pathway (83087); Olfactory Transduction Pathway (498); Pancreatic Secretion Pathway (169306); Pancreatic Secretion Pathway (169295); Stimuli-sensing Channels Pathway (771568); Transmembrane Transport Of Small Molecules Pathway (106572)

This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]

CLCA1: May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC. Belongs to the CLCR family. Protein type: Vesicle; Channel, chloride. Chromosomal Location of Human Ortholog: 1p22.3. Cellular Component: extracellular space; zymogen granule membrane; microvillus; integral to plasma membrane; plasma membrane. Molecular Function: chloride channel activity; metallopeptidase activity; metal ion binding. Biological Process: transport; calcium ion transport; chloride transport; proteolysis; transmembrane transport

48-Strip-Wells

435 USD

96-Strip-Wells

600