catalog number :
MBS083749
products type :
ELISA Kit
products full name :
Camel Mullerian Inhibiting Substance/Mullerian Hormone ELISA Kit
products short name :
[Mullerian Inhibiting Substance/Mullerian Hormone]
other names :
[muellerian-inhibiting factor; Muellerian-inhibiting factor; muellerian-inhibiting factor; anti-Muellerian hormone; Mullerian inhibiting factor; Mullerian inhibiting substance; muellerian-inhibiting substance; anti-Mullerian hormone; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance]
products gene name :
[MIS/AMH]
other gene names :
[AMH; AMH; MIF; MIS; MIF; AMH; MIS]
uniprot entry name :
MIS_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MISAMH (hereafter termed "analyte") in undiluted original Camel body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_000470.2
ncbi gb acc num :
NM_000479.3
ncbi mol weight :
59,195 Da
ncbi pathways :
ALK2 Signaling Events Pathway (137983); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475); CAMP Signaling Pathway (1017634); CAMP Signaling Pathway (1019520)
ncbi summary :
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: extracellular space; cytoplasm; extracellular region. Molecular Function: growth factor activity; hormone activity; transforming growth factor beta receptor binding; receptor binding. Biological Process: sex determination; response to drug; Mullerian duct regression; cell-cell signaling; gonadal mesoderm development; preantral ovarian follicle growth; sex differentiation; response to organic cyclic substance; urogenital system development; activation of NF-kappaB transcription factor; aging. Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
size4 :
10x96-Strip-Wells