catalog number :
MBS077381
products type :
ELISA Kit
products full name :
Cat Dermatan Sulfate ELISA Kit
products short name :
[Dermatan Sulfate]
other names :
[dermatan-sulfate epimerase; Dermatan-sulfate epimerase; dermatan-sulfate epimerase; DS epimerase; chondroitin-glucuronate 5-epimerase; squamous cell carcinoma antigen recognized by T-cells 2; dermatan sulfate epimerase; Chondroitin-glucuronate 5-epimerase; Squamous cell carcinoma antigen recognized by T-cells 2]
products gene name :
[DS]
other gene names :
[DSE; DSE; DSEP; DSEPI; SART2; EDSMC2; SART-2; SART2; DS epimerase; SART-2]
uniprot entry name :
DSE_HUMAN
storage stability :
Store all reagents at 2-8 degree C
ncbi acc num :
NP_001074445.1
ncbi gb acc num :
NM_001080976.1
ncbi mol weight :
109,773 Da
ncbi pathways :
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Dermatan Sulfate Biosynthesis Pathway (645310); Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (82982); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (356); Glycosaminoglycan Metabolism Pathway (645297); MPS I - Hurler Syndrome Pathway (685537); MPS II - Hunter Syndrome Pathway (685538); MPS IIIA - Sanfilippo Syndrome A Pathway (685539)
ncbi summary :
The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
SART2: Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Belongs to the dermatan-sulfate isomerase family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum; EC 5.1.3.19; Isomerase; Glycan Metabolism - chondroitin sulfate biosynthesis. Chromosomal Location of Human Ortholog: 6q22. Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum; integral to membrane. Molecular Function: chondroitin-glucuronate 5-epimerase activity. Biological Process: chondroitin sulfate metabolic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; heparan sulfate proteoglycan biosynthetic process; pathogenesis; dermatan sulfate biosynthetic process. Disease: Ehlers-danlos Syndrome, Musculocontractural Type 2
size4 :
10x96-Strip-Wells